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Biochemistry and Physiology of Plants
ETH Zurich, LFW D46.1
Universitätsstr. 2
CH-8092 Zurich
Switzerland
Tel: +41 +44 632 38 44
Fax: +41 +44 632 10 44
E-mail:
ffreimoser "at" ethz.ch
The focus of the research in
our group is a simple
molecule: inorganic
polyphosphate (poly P).
Poly P is a linear polymer that consists of a variable number of
phosphate residues
(from three to more than a thousand) that are
linked by energy-rich phosphoanhydride bonds. It has been detected
in all organisms and living cells and was found in many organelles.
In eukaryotes, poly P is particularly
prominent in fungi, algae and trypanosomatids.
Poly P serves as a phosphate and energy store and regulates
enzymes, chromatin condensation
and translation. Poly P is also involved in bacterial pathogenicity,
survival during stationary phase in
bacteria and yeast, or the adaptation to alkaline and osmotic stress.
In the slime mold Dictyostelium discoideum, poly P regulates
development and predation behaviour, and in humans blood coagulation is
accelerated and fibrinolysis is delayed by poly P.
In our group we study poly P metabolism and functions in eukaryotes and
we work mostly with yeast, filamentous fungi and algae. If you
would like to learn more about our research
or our group please visit our other pages. Or
visit the website of the whole group
of Prof. Amrhein, of which our lab is a part.
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and drawings,
are licensed under a Creative
Commons License except when noted. Commercial use or alteration of
any material
from this site is illegal without a written permission from Florian
Freimoser. Any
content from this site may be distributed for non-commercial purposes
provided the
authorship is clearly acknowledged.
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